GABAB receptor phosphorylation regulates KCTD12-induced K+ current desensitization
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چکیده
منابع مشابه
GABAB receptor phosphorylation regulates KCTD12-induced K+ current desensitization
GABAB receptors assemble from GABAB1 and GABAB2 subunits. GABAB2 additionally associates with auxiliary KCTD subunits (named after their K(+) channel tetramerization-domain). GABAB receptors couple to heterotrimeric G-proteins and activate inwardly-rectifying K(+) channels through the βγ subunits released from the G-protein. Receptor-activated K(+) currents desensitize in the sustained presence...
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ژورنال
عنوان ژورنال: Biochemical Pharmacology
سال: 2014
ISSN: 0006-2952
DOI: 10.1016/j.bcp.2014.07.013